The ability to detect and quantify apoptosis, to understand its biochemistry, and to identify its regulatory genes and proteins is crucial to biomedical research. In Apoptosis: Methods and Protocols, Second Edition, expert researchers describe the techniques to best investigate the critical steps involved in the apoptotic process. Presented from several different research perspectives, the volume contains sections covering detection of apoptosis, detection of non-apoptotic cell death, modifications of apoptotic proteins during apoptosis, the analysis of its major regulators, as well as analysis of apoptosis in different organs and in model organisms. Written in the highly successful Methods in Molecular Biology ™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Comprehensive and cutting-edge, Apoptosis: Methods and Protocols, Second Edition constitutes a key technical reference to the significant methodologies used in the field, and offers beginners and experienced researchers powerful tools to illuminate the phenomena of programmed cell death.
Publisher: Humana Press Inc.
Number of pages: 400
Weight: 1173 g
Dimensions: 260 x 193 x 28 mm
Edition: 2nd ed. 2009
From the reviews of the second edition:"Provides step-by-step protocols for identifying apoptotic cells and analyzing their role in normal tissue development and disease. ... The book is written primarily for basic science and clinical researchers (graduate students, postdoctoral fellows, scientists) ... . Biomedical researchers working in radiation biology, pharmacology, and molecular pathology also will value this book because of its focus on apoptosis in various organs including the heart and brain. ... This beautiful up-to-date synthesis of information about the analysis of apoptosis is filled with practical information." (Bruce A. Fenderson, Doody's Review Service, July, 2010)
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