• Sign In
  • Help
  • My Basket0
Angiogenesis and Anti-Angiogenesis in Hematological Malignancies (Hardback)
  • Angiogenesis and Anti-Angiogenesis in Hematological Malignancies (Hardback)
zoom

Angiogenesis and Anti-Angiogenesis in Hematological Malignancies (Hardback)

(author)
£109.99
Hardback 114 Pages / Published: 20/01/2014
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket

Check Marketplace availability

It has been generally accepted that angiogenesis is involved in the pathogenesis of hematological malignancies, like acute and chronic leukemia, lymphoma, myelodysplastic syndromes, myeloproliferative neoplasms and multiple myeloma. The extent of angiogenesis in the bone marrow has been correlated with disease burden, prognosis and treatment outcome. Reciprocal positive and negative interactions between tumor cells and bone marrow stromal cells, namely hematopoietic stem cells, fibroblasts, osteoblasts/osteoclasts, endothelial cells, endothelial progenitor cells, T cells, macrophages and mast cells, mediated by an array of cytokines, receptors and adhesion molecules, modulate the angiogenic response in hematological tumors. More recently, it has been emphasized the pro-angiogenic role of the so called "vascular niche", indicating a site rich in blood vessels where endothelial cells and mural cells such as pericytes and smooth muscle cells create a microenvironment that affects the behavior of several stem and progenitor cells, in hematological malignancies.

Publisher: Springer
ISBN: 9789401780346
Number of pages: 114
Weight: 362 g
Dimensions: 235 x 155 x 13 mm
Edition: 2014 ed.


MEDIA REVIEWS

From the reviews:

"This book will appeal mainly to researchers in the field of angiogenesis/antiangiogenesis, and students. ... This is a comprehensive book on an important area of cancer research that is often overshadowed by literature on solid tumors. It will be most helpful for researchers looking for information on the subject, but it also enlightens practitioners on the mechanisms of action of some common treatments for hematological malignancies." (Leslie Popplewell, Doody's Book Reviews, June, 2014)

You may also be interested in...

Radical Remission
Added to basket
The Cancer-Fighting Diet
Added to basket
When I Die
Added to basket
£8.99
Paperback
Medicine Hands
Added to basket
£29.99
Paperback
Bone Cancer
Added to basket
£110.00
Hardback
Beat Cancer
Added to basket
£14.99
Paperback
Physics for Clinical Oncology
Added to basket
The Emperor of All Maladies
Added to basket
Survival Lessons
Added to basket
Cancer
Added to basket
£12.50
Paperback
The Biology of Cancer
Added to basket
Cancer: A Very Short Introduction
Added to basket
Oxford Handbook of Clinical Haematology
Added to basket
£34.99
Part-work (fascículo)
Laws of Medicine
Added to basket
B is for Breast Cancer
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.