A Prescription for Change: The Looming Crisis in Drug Development (Hardback)
  • A Prescription for Change: The Looming Crisis in Drug Development (Hardback)
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A Prescription for Change: The Looming Crisis in Drug Development (Hardback)

(author)
£44.95
Hardback 336 Pages / Published: 30/09/2016
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The introduction of new medicines has dramatically improved the quantityand quality of individual and public health while contributing trillions ofdollars to the global economy. In spite of these past successes-and indeedbecause of them-our ability to deliver new medicines may be quicklycoming to an end. Moving from the twentieth century to the present, APrescription for Change reveals how changing business strategies combinedwith scientific hubris have altered the way new medicines are discovered,with dire implications for both health and the economy.

To explain how we have arrived at this pivotal moment, Michael S. Kinchrecounts the history of pharmaceutical and biotechnological advances in thetwentieth century, relating stories of the individuals and organizations thatushered in the modern era of translational medicine. He shows that an acceleratingcycle of acquisition and downsizing is cannibalizing the very infrastructurethat had fostered the introduction of innovative new medicines.As Kinch demonstrates, the dismantling of the pharmaceutical and biotechnologicalresearch and development enterprises could also provide opportunitiesto innovate new models that sustain and expand the introduction ofnewer and better breakthrough medicines in the years to come.

Publisher: The University of North Carolina Press
ISBN: 9781469630625
Number of pages: 336
Weight: 653 g
Dimensions: 229 x 152 x 30 mm


MEDIA REVIEWS
Begins with the history of drug development from ancient times up to 2016. . . . Packs in detail, but keeps it readable.--Compression


An informative and fascinating read for anyone with an interest in the drug discovery process, scientists, healthcare professionals, investors, regulators, or those who just want to see our economy flourish and public health to be improved for the global benefit to society or just to protect an individual 401K plan. . . . Highly recommend this well-written book as a must read for anyone with the slightest interest in how the drug discovery process impacts our economy and public health.--Doody's Reviews


A thorough review of the history of the development of every drug to receive FDA approval. . . . [Kinch] brings to this book many decades of research and harrowing personal experience with pharma.--EurekAlert!


Traces the history of the pharmaceutical and biotechnology industries and describes the evolution of the scientific, regulatory, social, and marketing forces that are compromising contemporary drug developments . . . . Well explained and illustrated with useful anecdotes.--Science Magazine


A cogent and comprehensive view of where the drug industry is today and how it got there.--Health Affairs

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